Members of Chikayoshi Sumi Labolatory Access Guide Published papers books
Department of Information & Communication Sciences
Faculty of Science & Technology/Graduate Division of Science &
Technology
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Our
Research Targets
We are conducting development of low-invasive diagnosis/treatment modalities
for various cancerous diseases and various functional disorders. Suitable
utilization of electromagnetic waves and/or mechanical waves will allow
providing us the clinical modalities together with contributions to cellular
engineering/measurement system engineering.
Our current research targets are briefly as follows:
1) Diagnosis: Elasticity imaging, Elastography
Ultrasound imaging,
Infrared light imaging,
NMR imaging,
SQUID imaging,
OCT,
Measurement and analysis of various
self-emanating signals, etc.
2) Cure: Hyperthermia,
Artificial organs,
Drug deliverly systems, etc.
Thus, we are working at transdisciplinary field.
Samples
of Elasticity Images, i.e., Shear Modulus and Strain Images
Sample 1: Breast
scirrhous carcinoma tissue shear modulus images of a 48.0 mm x 44.6 mm
ROI spreading from 17.1 to 65.1 mm in the axial direction. The reference
material (thickness: 40.0 mm) covering the volunteer skin surface has a
shear modulus of 1.2 x 106 N/m2.
B-mode image under pre-compression (upper left), and reconstructed absolute
shear modulus images in the log gray scale (upper right, Inverse shear
moduli; lower left, shear moduli; lower right, shear moduli with a high
resolution). The highest value: 2.35 x 107N/m2.
Upper right (DR: 65.4 dB, lowest value: 1.26 x 104 N/m2,
bright region relatively low shear modulus value.), lower left and lower
right (DR: 54.9 dB, lowest value 4.21 x 104 N/m2,
bright region high shear modulus.).
Strain image in a log gray scale with a dynamic range of 14.4 dB,in
which the bright region indicates that the region is relatively soft and
vice versa. As shown in this image, the multiple-layer
structure of fat and muscle is favorably visible.
Conventional B-mode image (Nominal frequency: 3.5 MHz).
Sample 2: Images obtained on the fresh in vitro pork rib (ROI size: 20.0 mm x 72.8
mm).
Strain image in a log gray scale with a dynamic range of 11.1 dB. The reference
material attached on her skin surface has a shear modulus of 2.8 x 105
N/m2, and this image exhibits the spatial
variation of shear modulus from 4.1 x 104 N/m2 to 5.2
x 105 N/m2.
Also in this elasticity image, the fat seems to
be favorably visible (lower left area). Namely,
it should be rather soft. However, interestingly
in this image, the mammary glands being stiffer
seems to be visualized below the skin surface and also at the lower right
area though it's difficult to detect them from the conventional B-mode
image.
B-mode image (Nominal frequency: 3.5 MHz).
Sample 3: Images obtained on the in vivo breast tissue (healthy 37-years-old, ROI size: 19.9
mm x 30.0 mm).